|
KMID : 1195620090020020078
|
|
Clinical and Experimental Otorhinolaryngology
2009 Volume.2 No. 2 p.78 ~ p.84
|
|
|
Clinical Efficacy of Primary Tumor Volume Measurements: Comparison of Different Primary Sites
|
|
Chung Eun-Jae
Lee Nam-Joon
Baek Seung-Kuk
Kwon Soon-Young
Woo Jeong-Soo
Jung Kwang-Yoon
|
|
|
Abstract
|
|
|
Objectives: The purpose of study was to determine the clinical efficacy of primary tumor volume measurements of different primary sites in the oropharynx compared to the oral cavity.
Methods: A retrospective analysis of 85 patients with oral cavity or oropharynx cancer. The tumor area was manually outlined from axial magnetic resonance (MR) series. The software calculated the tumor volumes, automatically. The values of the primary tumor volumes were then subdivided into separate groups (≤3,500 mm3, >3,500 mm3).
Results: The prognostic indicators were the cT and cN (oral cavity); age, primary site, cT, cN, and primary tumor volume (oropharynx) on the univariate analysis. There was no significant prognostic factor for oral cavity cancer on the multivariate analysis. Primary site, cN, and primary tumor volume were independent prognostic indicators for oropharynx cancer by multivariate analysis.
Conclusion: Primary tumor volume measurement is a reliable way to stratify outcome, and make up for the weak points in the American Joint Committee on Cancer staging system with oropharynx cancer.
|
|
|
KEYWORD
|
|
|
Tumor volume, Prognosis, Lymphatic metastasis, Mouth neoplasm, Oropharyngeal neoplasm
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
   
|
|